沈峰
長聘副教授🤷🏿，博士生導師。2005年畢業於清華大學化學系，2010年獲得美國芝加哥大學化學博士學位。博士期間主要的研究方向為1)微流控芯片模擬血管的生物結構及時空動力學研究血液凝結機理🏭👩💼；2）新型的微流控芯片用於高通量基因檢測，數字PCR基因定量👩❤️💋👨，數字恒溫基因擴增🫰🚶🏻♀️。2010-2011繼續在芝加哥大學進行博士後研究，期間研發了新型的HIV/HCV病毒定量系統🧑🏻🔧。於2011年共同創立了滑動芯片科技公司，並擔任公司的研發總監領導研發了新一代的小型高集成分子診斷系統。在Nature Chemical Biology, PNAS, JACS, Angewandte Chemie, Analytical Chemistry, Lab on a Chip, Advanced Biosystems等雜誌發表了三十余篇學術論文並獲得了多項美國及中國專利。
2001-2005 清華大學 化學系
2005-2010 芝加哥大學 化學系
2011-2017 泰利斯醫療儀器公司（美國） 創始人/研發總監/產品總監
2018- 2023 意昂4平台 意昂4体育平台 長聘教軌副教授
2014- 至今 意昂4平台 意昂4体育平台 長聘副教授
主要的研究方向為用於生物學研究及臨床診斷的新型微流控芯片，包括但不局限於：
39. Yang Luo, Qixin Hu, Yan Yu, Weiyuan Lyu, Feng Shen* Experimental Investigation of Confinement Effect in Single Molecule Amplification via Real-time Digital PCR on a Multivolume SlipChip, Analytica Chimica Acta, in press
38. Jiajie Zhang, Lei Xu, Zheyi Sheng, Jiayi Zheng, Weiyu Chen, Qixin Hu, Feng Shen* Combination-lock SlipChip Integrating Nucleic Acid Sample Preparation and Isothermal LAMP Amplification for the Detection of SARS-CoV-2, ACS Sensors, 2024, 9, 2, 646-653(Cover Issue)
37. Yan Yu, Sheng Wang, Yang Luo, Chang Gu, Xin Shi,* Feng Shen,* Quantitative Investigation of Methylation Heterogeneity by Digital Melting Curve Analysis on a SlipChip for Atrial Fibrillation. ACS Sensors, 2023, 8, 9, 3595–3603
36. Weiyuan Lyu, Jingwei Yi, Qingsheng Guo, Yao Wang, Jiajie Zhang, Tong Sun, Haoji Ma, Tingting Tang, Xueling Quan, Hong Xu,* Feng Shen,* Hongchen Gu Multiplex Digital Immunoassays with Reduced Pre-partition Reaction via Massively Parallel Reagent Delivery on a Bead-based SlipChip. ACS Nano, 2023, 17, 13, 12641–12651
35. Xiang Li, Qixin Hu, Xu Liu, Jianfang Liu, Nannan Wu, Feng Shen* Rapid Bacteriophage Quantification by Digital Biosensing on a Slip-Chip Microfluidic Device. Analytical Chemistry, 2023, 95, 22, 8632–8639
34. Qixin Hu,# Fariha Kanwal,# Weiyuan Lyu, Jiajie Zhang, Xu Liu, Kai Qin,* Feng Shen* Multiplex Digital PCR on a Droplet Array SlipChip for Analysis of KRAS Mutations in Pancreatic Cancer. ACS Sensors, 2023, 8, 114-121
33. Xiang Li, Xu Liu, Ziqing Yu, Yang Luo, Qixin Hu, Zhenye Xu, Jia Dai, Nannan Wu,* Feng Shen* Combinatorial Screening SlipChip for Rapid Phenotypic Antimicrobial Susceptibility Testing. Lab on a Chip, 2022, 22, 3952-3960
32. Xu Liu, Xiang Li, Nannan Wu, Yang Luo, Jiajie Zhang, Ziqing Yu, Feng Shen* Formation and Parallel Manipulation of Gradient Droplets on a Self-partitioning SlipChip for Phenotypic Antimicrobial Susceptibility Testing. ACS Sensors, 2022, 7, 1977-1984 (Cover Issue)
31. Ziqing Yu,# Lei Xu,# Weiyuan Lyu, Feng Shen* Parallel Multistep Digital Analysis SlipChip Demonstrated with the Quantification of Nucleic Acid by Digital LAMP-CRISPR. Lab on a Chip, 2022, 22, 2954-2961 (Cover Issue)
30. Jin Li,# Chang He,# Haijun Qu,# Feng Shen,* Jian Ye* Five-dimensional unclonable anticounterfeiting orthogonal Raman Labels. Journal of Materials Chemistry C, 2022, 10, 7273-7282
29. Jin Li, Fugang Liu, Chang He, Feng Shen, Jian Ye* Orthogonal gap-enhanced Raman tags for interference-free and ultrastable surface-enhanced Raman scattering. Nanophotonics, 2022, 0689
28. Yan Yu, Ziqing Yu, Xufeng Pan, Lei Xu, Rui Guo, Xiaohua Qian, Feng Shen*, Multiplex Digital PCR with Digital Melting Curve Analysis on a Self-partitioning SlipChip. Analyst, 2022, 147, 625-633
27. Weiyuan Lyu, Jiajie Zhang, Yan Yu, Lei Xu, Feng Shen*, Slip Formation of a High-Density Droplet Array for Nucleic Acid Quantification by Digital LAMP with a Random-Access System. Lab on a Chip, 2021, 21, 3086-3093
26. Chang Gu, Shi Xin, Wenli Qiu, Zhenyu Huang, Yan Yu, Feng Shen*, Yumei Chen*, Xufeng Pan*, Comprehensive analysis of the prognostic role and mutational characteristics of m6A related genes in lung squamous cell carcinoma. Front. Cell Dev. Biol. 2021, 9, 661792
25. Lei Xu,# Haijun Qu,# Daniel Garcia Alonso, Ziqing Yu, Yan Yu, Yejing Shi, Chunlan Hu, Tongyu Zhu, Nannan Wu,* Feng Shen*🤛🏻，Portable Integrated Digital PCR System for the Point-of-Care Quantification of BK Virus from Urine Samples. Biosensors and Bioelectronics 2021, 175, 112908
24. Chang Gu，Xin Shi，Chenyang Dai，Feng Shen🫃🏻，Gaetano Rocco，Jiafei Chen，Zhengyu Huang👯，Chunji Chen🥈，Chuan He，Tao Huang，Chang Chen*, RNA m6 A Modification in Cancers: Molecular Mechanisms and Potential Clinical Applications. The Innovation Volume 1, Issue 3, 25 November 2020, 100066
23. Ziqing Yu,# Weiyuan Lyu,# Mengchao Yu,# Qian Wang,# Haijun Qu, Rustem F. Ismagilov, Xu Han, Dongmei Lai,* Feng Shen*, Self-partitioning SlipChip for Slip-induced Droplet Formation and Human Papillomavirus Viral Load Quantification with Digital LAMP. Biosensors and Bioelectronics 2020, 155 (2020) 112107
22. Haijun Qu, Mengchao Yu, Wenbin Du, Lei Xu, Weiyuan Lyu, Feng Shen, Slip Molding for Precision Fabrication of Microparts. Langmuir 2020, 36, 585-590 (Cover Issue)
21. Weiyuan Lyu, Mengchao Yu, Haijun Qu, Ziqing Yu, Wenbin Du, Feng Shen, Slip-driven Microfluidic Devices for Nucleic Acid Analysis. Biomicrofluidics 2019, 4,041502
20. Mengchao Yu, Xiaoying Chen, Haijun Qu, Liang Ma, Lei Xu, Weiyuan Lv, Hua Wang, Rustem F. Ismagilov, Min Li*, Feng Shen*, Multistep SlipChip for the Generation of Serial Dilution Nanoliter Arrays and Hepatitis B Viral Load Quantification by Digital Loop Mediated Isothermal Amplification. Analytical Chemistry 2019, 91, 14, 8751-8755 (Cover issue)
19. García Alonso, D.; Yu, M.; Qu, H.; Ma, L.; Shen, F. Advances in Microfluidics-Based Technologies for Single Cell Culture. Advanced Biosystems 2019, 1900003, 1–10
18. Nie, M.; Zheng, M.; Li, C.; Shen, F.; Liu, M.; Luo, H.; Song, X.; Lan, Y.; Pan, J. Z.; Du, W. Assembled Step Emulsification Device for Multiplex Droplet Digital Polymerase Chain Reaction. Analytical Chemistry 2019, 91 (3), 1779–1784
17. Feng Shen, Methods in Molecular Biology 2016
16. Stefano Begolo, Feng Shen, and Rustem F. Ismagilov, Lab Chip 2013 13: 4331-4342 (Cover issue)
15. Bing Sun, Feng Shen, Stephanie E. McCalla, Jason E. Kreutz, Mikhail A. Karymov, and Rustem F. Ismagilov, Analytical Chemistry 2013 85: 1540-1546
14. Feng Shen, Bing Sun, Jason E. Kreutz, Elena K. Davydova, Wenbin Du, Poluru L. Reddy, Loren J. Joseph, and Rustem F. Ismagilov, Journal of the American Chemical Society 2011 133: 17705-17712
13. Jason E. Kreutz, Todd Munson, Toan Huynh, Feng Shen, Wenbin Du, and Rustem F. Ismagilov, Analytical Chemistry 2011 83: 8158-8168
12. Feng Shen, Elena K. Davydova, Wenbin Du, Jason E. Kreutz, Olaf Piepenburg, and Rustem F. Ismagilov, Analytical Chemistry 2011 83:3533-3540
11. Feng Shen, Wenbin Du, Jason E. Kreutz, Alice Fok, and Rustem F. Ismagilov, Lab Chip 2010 10: 2666-2672 (Cover issue)
10. Feng Shen, Wenbin Du, Elena K. Davydova, Mikhail A. Karymov, Janmajay Pandey, and Rustem F. Ismagilov, Analytical Chemistry 2010 82:4606-4612
9. Feng Shen, Rebecca R. Pompano, Christian J. Kastrup, and Rustem F. Ismagilov, Biophysical Journal 2009 97: 2137-2145
8. Christian J. Kastrup, James Q. Boedicker, Andrei P. Pomerantsev, Mahtab Moayeri, Yao Bian, Rebecca R. Pompano, Timothy R. Kline, Patricia Sylvestre, Feng Shen, Stephen H. Leppla, Wei-Jen Tang, and Rustem F. Ismagilov, Nature Chemical Biology 2008 4:742-750
7. Feng Shen, Christian J. Kastrup, Ying Liu, and Rustem F. Ismagilov, Arterioscler. Thromb. Vasc. Biol. 2008 28: 2035-2041
6. Feng Shen, Christian J. Kastrup, and Rustem F. Ismagilov, Thrombosis Research. 2008;122: S27-S30
5. Christian J. Kastrup, Feng Shen, Matthew K. Runyon, and Rustem F. Ismagilov, Biophysical Journal 2007 93:2969-2977
4. Christian J. Kastrup, Feng Shen, and Rustem F. Ismagilov, Angew. Chem. Int. Ed. 2007 46: 3660-3662 (Cover issue)
3. Christian J. Kastrup, Matthew K. Runyon, Feng Shen, and Rustem F. Ismagilov, Proceedings of the National Academy of Sciences 2006 103:15747-15752 (Cover issue)
2. Xueshu Li, Feng Shen, Hua Fu, Yuyang Jiang, Yufen Zhao. Synlett. 2006; 4: 630-632
1. Xueshu Li, Dongwei Zhang, Hai Pang, Feng Shen, Hua Fu, Yuyang Jiang, Yufen Zhao. Organic Letters. 2005; 7: 4919-4922
本科課程😠：《醫療診斷前沿技術與創新應用》
研究生課程👈🏽：《微流控原理、應用與實踐》
郵箱地址🏧：feng.shen@sjtu.edu.cn
辦公地址：教三樓 213室
網址：https://www.x-mol.com/groups/shenfeng_sjtu
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