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  馬斌

  副教授，博士生導師。2005年獲蘭州大學生物科學專業學士學位。 2007年獲得荷蘭格羅寧根大學醫學製藥學專業優等碩士學位(cum laude)⛹🏽。2012年獲荷蘭特文特大學博士學位，並獲得2011年度國家優秀自費留學生獎學金🧑‍🎓💈。2013年至2015年在瑞士蘇黎世大學及附屬兒童醫院從事博士後研究工作🕵🏻‍♀️。2015年10月加入意昂4体育平台🛣。2016年獲得上海高校青年東方學者稱號。

2007/10至2012/09, 荷蘭特文特大學, 細胞與分子生物學, 博士

2005/09至2007/07, 荷蘭格羅寧根大學, 醫學製藥學, 碩士

2001/09至2005/06, 蘭州大學, 生物科學, 學士

2015/10至現在, 意昂4平台, 意昂4体育平台, 副研究員

2014/02至2015/06, 瑞士蘇黎世大學附屬兒童醫院, 博士後

2013/01至2014/08, 瑞士蘇黎世大學, 博士後

• Gui L^#, Chen K^#, Yan J, Chen P, Gao WQ, Ma B*. Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity. Cell Rep Med 2025; 6(2): 101913. ^#Co-first author; *Corresponding author
  
• Gui L^#, Wang Z^#, Lou W^#, Yekehfallah V, Basiri M, Gao WQ, Wang Y*, Ma B*. Comparative evaluation of antitumor effects of TNF superfamily costimulatory ligands delivered by mesenchymal stem cells. Int Immunopharmacol 2024; 126: 111249. ^#Co-first author; *Corresponding author
  
• Yekehfallah V, Pahlavanneshan S, Sayadmanesh A, Momtahan Z, Ma B*, Basiri M*. Generation and functional characterization of PLAP CAR-T cells against cervical cancer cells. Biomolecules 2022; 12: 1296. *Corresponding author
  
• Ji L, Peng P, Gui L, Yuan P, Qian W, Wang Y, Gao WQ*, Ma B*.  CD24 is a superior immunotherapeutic target to PD-1 in a mouse model of Helicobacter-induced gastric cancer. Gastro Hep Advances 2022; 1(1):79-82. *Corresponding author
• Yan J, Yuan P, Gui L, Wang Z, Yin P, Gao WQ, Ma B*. CCL28 downregulation attenuates pancreatic cancer progression through tumor cell-intrinsic and -extrinsic mechanisms. Technol Cancer Res Treat 2021; 20:15330338211068958. *Corresponding author
  
• Wang C^#, Yan J^#, Yin P, Gui L, Ji L, Ma B*, Gao WQ*. β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer. OncoImmunology 2020; 9(1): e1809947. ^#Co-first author; *Corresponding author
• Yin P, Gui L, Wang C, Yan J, Liu M, Ji L, Wang Y, Ma B*, Gao WQ*. Targeted delivery of CXCL9 and OX40L by mesenchymal stem cells elicits potent antitumor immunity. Mol Ther 2020; 28(12):2553-63.  *Corresponding author 
• Ji L, Qian W, Gui L, Ji Z, Yin P, Lin GN, Wang Y, Ma B*, Gao WQ*. Blockade of β-catenin-induced CCL28 suppresses gastric cancer progression via inhibition of Treg cell infiltration. Cancer Res 2020; 80(10):2004-16. *Corresponding author
• Ma B, Hottiger MO. Crosstalk between Wnt/β-catenin and NF-κB signaling during inflammation. Front Immunol 2016; 7:378.
• Ma B, Fey M, Hottiger MO. WNT/β-catenin signaling inhibits CBP-mediated RelA acetylation and expression of a proinflammatory subset of NF-κB target genes. J Cell Sci 2015; 128:2430-2436.
• Ma B, Zhong L, van Blitterswijk CA, Post JN, Karperien M. T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling. J Biol Chem 2013; 288:17552-8.
• Ma B, van Blitterswijk CA, Karperien M. A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes. Arthritis Rheum 2012; 64:2589-600.
• Ter Elst A^#, Ma B^#, Scherpen FJG, de Jonge HJ, Douwes J, Wierenga AT, Schuringa JJ, Kamps WA, de Bont ES. Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia. Cancer Res 2011; 71:2761-71. ^#Co-first author

免疫疾病與腫瘤免疫基礎 (32學時，研究生)

免疫與健康 (32學時，本科生)